Mpox Vaccine

Available to any person who wants protection from mpox infection.

Mpox Vaccine

SF vaccine sites are now providing the second dose of the mpox (Jynneos) vaccine to people who are at least 28 days from receiving their first dose.

Mpox vaccines are available by appointment at healthcare providers and clinics throughout the city, including Kaiser Permanente (call 415-833-9999) and UCSF (call 415-502-3566). You do not need to be a Kaiser or UCSF Patient. People should seek the second dose from their usual health care provider, regardless of where their initial dose was obtained.  

We are working with local community-based organizations to provide the vaccine to those who may not have access to the walk-in clinics or a healthcare provider. We will continue to keep the community updated on additional allocations of vaccines and access points. 

The goal is for everyone who wants a vaccine to receive a vaccine. 

Mpox Vaccine Administration Update

SFDPH & partner sites are now offering first and second doses of the mpox vaccine though subcutaneous injection for eligible people who prefer this method over an intradermal injection. Both methods provide the same amount of protection against mpox. Click here to learn more about both methods. No matter the choice you make, it is important to get your second dose of the mpox vaccine if it has been at least 28 days since you received your first dose, to be fully vaccinated against mpox. 


Anyone who wants protection from mpox infection may receive mpox vaccine

There is no shortage of mpox vaccine now, and so the San Francisco Department of Public Health (SFDPH) and many other health departments in California have removed all the eligibility criteria.  Anyone who may be at risk of getting mpox can now receive the JYNNEOS vaccine to prevent mpox. There is no need to prove eligibility for the vaccine.  

Some people are still at higher risk of getting mpox than others, and those persons are now considered priority groups that are recommended to get the JYNNEOS vaccine.

SFDPH recommends mpox vaccination with JYNNEOS for these priority groups:  

  • Persons who have had a known exposure to mpox and need post-exposure prophylaxis (PEP)
  • People with occupational (job-related) risk, including
    • Healthcare workers likely to collect laboratory specimens from patients with mpox
    • Persons working in sexual health clinics
    • Persons working in clinical settings that serve at-risk populations
    • Any occupational group recommended by Advisory Committee on Immunization Practices (ACIP) to get the vaccine
  • Any person living with HIV, especially those with risk of complications of mpox, such as persons with a CD4 count <350/mm3, an unsuppressed viral load, or who have had an opportunistic infection
  • Any man, trans person, or nonbinary person who has sex with men, trans persons, or nonbinary persons
  • Persons who are taking or are eligible to take HIV PrEP
  • Sex workers
  • Sexual contacts of any persons included above
  • Persons who have had close contact, within the past 6 months, with someone with suspected or confirmed mpox
  • Persons who had sex or close contact, within the past 6 months, at a venue or event, or within a social group, with a suspected or confirmed mpox case. This includes persons who received notice from a venue or event of a potential exposure.
  • Persons diagnosed, in the past 3 months, with a bacterial sexually transmitted disease (for example: chlamydia, gonorrhea, syphilis)
  • Persons who expect to experience any of the above

Two doses of JYNNEOS should be received, with at least 4 weeks separation between doses. This helps ensure longer-term protection against mpox.

If it has been more than 4 weeks since the first dose, the second dose can be administered as soon as possible, and the series does not need to be restarted.    

Since no vaccine is 100 percent effective, it is important for individuals to reduce the risk of potential exposures to mpox both before and after vaccination. 

Mpox Vaccine Sites

People should seek the second dose from their health care provider, regardless of where their first dose was obtained.  

The vaccines, which includes first and second doses of Jynneos, is available  at various pop-up vaccination sites, neighborhood vaccine clinics and events at health system providers. 

Vaccine Sites

  • 24 and Capp St., Fridays and Saturdays, 9 am to 4 pm

  • 2401 Keith St., Tuesday through Saturday from 9am to 5 pm

  • 330 Ellis St., Thursdays, 1:00 to 4:45 pm

  • 1099 Sunnydale Ave, Mondays, 9:30 am to 4:30 pm

  • 701 Alabama St., Thursdays, 11:30 am to 2:30 pm
  • 400 Randolph St., every Friday from 9 am to 4:00 pm 

  • The vaccination clinic at ZSFG1001 Potrero, Building 30, Monday through Friday, 8 am to 4 pm 
  • 246 Eddy Street, Saturdays, 12:00pm - 3:45pm

  • 20 Norton St., Thursdays and Fridays, 11 am to 4:45 pm, Saturdays, 9:30 am to 3:30 pm

  • 1181 Golden Gate, Wednesdays and Saturdays, 10 am to 5:30 pm

The following locations have supplies of Jynneos vaccine by appointment only:    

  • Adult Immunization and Travel Clinic (AITC) patients: please make an online appointment at

  • SF City Clinic: call 628-217-6600

  • Strut patients: call 628-212-8038  

  • Kaiser Permanente patients and non-patients: call 415-833-9999  

  • SF Health Network patients: call your provider or health center directly 

  • UCSF patients and non-patients: call 415-502-3566 

How to get proof of Mpox vaccination


  • Check your medical record or ask your provider

    You can find it in your online health record under the immunization history section. If you don’t see it, ask your healthcare provider.  Your provider should have a record of vaccination dates and locations. They can also print your immunization record through the California Immunization Registry (CAIR)
  • Request a record from CAIR

    CAIR was not designed for a high volume of requests. Use this method if the above options are not possible. Requests may take up to 14 business days, so please plan ahead. The California Immunization Registry (CAIR) is a secure immunization information system for California. Fill out this form to get your record emailed to you. Travelers from outside the U.S. who get vaccinated in California may email the Help Desk to get the form. Residents of Alpine, Amador, Calaveras, Mariposa, Merced, San Joaquin, Stanislaus, and Tuolumne counties: Visit My Healthy Futures to get your immunization record.


When is it time for your second dose of MPX vaccine?

If this is your first dose, don’t forget to complete your 2nd dose! You should get your 2nd dose at 28 days or later after your first dose. You can set a reminder in your phone or mark your calendar. If you are not local, visit the MPX Vaccine Locator for locations near you.

Última actualización March 13, 2023