Monkeypox Vaccine

Demand for vaccine is high and supply extremely limited.

Monkeypox Vaccine

As supply dictates, the Monkeypox vaccine is available by appointment at clinics throughout the city, including Kaiser Permanente and UCSF. See sites below. 

The walk-in vaccination clinic located at ZSFG at 1001 Potrero, Building 30, will be open Monday, August 15 through Friday, August 19 from 8 am to 4 pm. No appointment is needed. We will update the community with additional hours as we receive more information about additional doses.

Medical providers Kaiser and UCSF will be providing doses via appointments and will serve both non-patients and patients. Please check their websites for appointments or call your provider for more information. 

DPH is working with local community-based organizations to provide the vaccine to those who may not have access to the walk-in clinic or a healthcare provider. We will continue to keep the community updated on additional allocations of vaccines and access points.

To date, we have received approximately 23,000 doses from the federal stockpile from the California Department of Public Health (CDPH). SFDPH requested 35,000 doses to begin to meet the need. 

This, unfortunately, means that someone may be eligible for a vaccine but unable to receive it immediately due to a lack of vaccine supply from the State and Federal governments. 

The goal is for everyone who wants a vaccine to receive a vaccine. 

We will let the community know as soon as we have more doses of the vaccine.

People who live and work in San Francisco are eligible for a Jynneos vaccine:  

  • Gay, bisexual, and other men or trans people who have sex with men, who have had more than 1 sexual partner in the past 14 days 
  • Sex workers of any sexual orientation or gender identity
  • Persons who have had close contact within the past 14 days with someone with suspected or confirmed monkeypox 
  • Persons who had close contact with others at a venue or event or within a social group in the past 14 days where a suspected or confirmed monkeypox case was identified. This includes persons who received notice from a venue or event of a potential exposure within the past 14 days
  • Laboratory workers who routinely perform monkeypox virus testing
  • Clinicians who have had a high-risk occupational exposure (e.g., examined monkeypox lesions or collected monkeypox specimens without using recommended personal protective equipment)

Jynneos Vaccine First Dose Priority

SFDPH and vaccine partners will prioritize first dose of Jynneos vaccine to as many at-risk people as possible and will defer second dose appointments until sufficient supply is received. Given the rapid increase of cases and very limited number of vaccines, this strategy will allow more people to receive a dose.

An additional (second) dose of the Jynneos vaccine is now available to people who have moderate to severe immune compromise as they may not develop immunity after just one dose. This includes people on active cancer treatment, people who are taking medicine to suppress the immune system, and people with advanced or untreated HIV infection, among other conditions. People should consult with their health provider on whether to seek an additional dose of the vaccine at this time. A doctor’s note will be required for an additional dose at the ZSFG clinic for people who are out-of-network.

According to the U.S. Food and Drug Administration, Jynneos is indicated for prevention of smallpox and monkeypox disease in adults. However, since no vaccine is 100 percent effective, it is important for individuals to reduce their risk of potential exposures to monkeypox both before and after being vaccinated. 

SFDPH and vaccine partners will notify the community when vaccine supply is available for second doses to complete the vaccine series. If a person receives one dose, a second dose can be administered without having to restart the series, even if the second dose is given after the minimum interval of four weeks.

Monkeypox Vaccine Sites

Drop-in vaccines for San Francisco residents who meet vaccine eligibility requirements:

Zuckerberg SF General Learning Center (ZSFG clinic), 1001 Potrero Avenue, Building 30, 2nd Floor, San Francisco, Monday, August 15 through Friday, August 19, 8 am to 4 pm.

The following locations have supplies of Jynneos vaccine by appointment only:   

  • Adult Immunization and Travel Clinic (AITC) patients call: 415-554-2625
  • Strut patients: call 628-212-8038 
  • Kaiser Permanente patients and non-patients: call 415-833-9999 
  • SF Health Network patients: call your provider or health center directly
  • UCSF patients and non-patients: call 415-502-3566
Last updated August 17, 2022

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