Moscone Center South COVID-19 Vaccine Site

Walk-thru high-volume site open to people who live or work in SF, who are 16 years and older.

By appointment after confirming location and eligibility.

Getting here

Moscone Center South is a walk-thru site.

It is centrally located in the SoMa neighborhood. The entrance is on Howard between 3rd and 4th streets. 


There is paid parking at the Fifth and Mission (Yerba Buena) Garage at 833 Mission Street. Rates are $3 to $5 per hour, depending on when you enter. See more details. Bike parking is also available at the garage.

You can be dropped off on Howard Street in front of Moscone.


Check-in is in the first floor lobby area. Site ambassadors will direct you when you arrive.

The site is wheelchair accessible. Moscone also has wheelchairs available. If you need a wheelchair, ask onsite staff. They will bring a wheelchair to you.

ASL video remote interpreting is available at this location.

Ride Paratransit for free, to and from your appointment. Paratransit SF Access van riders must call to make a trip reservation. Tell the operator that you are going to get a vaccine. Paratransit taxi riders will have $60 loaded onto their taxi debit card. The funds are valid for up to 6 months. See the SFMTA website for more information.

Public transportation

Scarves, ski masks, balaclavas, or bandanas are not allowed on any public transportation (or waiting for it). See SF guidance on traveling on public transit.

From Powell Street BART Station

  1. Exit to 4th and Market Streets.
  2. Turn right on 4th.
  3. Walk 2 blocks south to Howard and turn left. The Moscone Center is located on the 700 block of Howard Street.
  4. You'll find Moscone South on your right.


From Montgomery Street BART Station

  1. Exit to New Montgomery and Market Streets. Walk 2 blocks west on Market Street.
  2. Turn right on 3rd.
  3. Walk 2 blocks south to Howard and turn right. The Moscone Center is located on the 700 block of Howard Street.
  4. You'll find Moscone South on your left.



Ride Muni for free, to and from your appointment. Show your vaccine card or proof of your appointment. You can also show an email confirmation or a photo of your card.


From Caltrain (4th and King)

You can take Caltrain from the Peninsula.

  1. Exit onto 4th St.
  2. Walk north on 4th for 5 blocks.
  3. Turn right on Howard. Moscone South will be on your right.



Ferry service is available from Alameda, Oakland, Vallejo, Larkspur and Sausalito. From San Francisco's Ferry Terminal, connect to the BART or Muni options.


CA COVID-19 hotline

The hotline operates Monday to Friday, 8 am to 8 pm. Saturday and Sunday, 8 am to 5 pm.

Moscone Center South
747 Howard Street
San Francisco, CA 94103