MPX Vaccine

Available to people of any age or gender who may have been exposed. We are now giving second doses after 28 days.

MPX Vaccine

SF vaccine sites are now providing the second dose of the MPX (Jynneos) vaccine to people who are at least 28 days from receiving their first dose. However, all healthcare providers will still reserve some vaccine for first doses.   

MPX vaccines are available by appointment at healthcare providers and clinics throughout the city, including Kaiser Permanente (call 415-833-9999) and UCSF (call 415-502-3566). You do not need to be a Kaiser or UCSF Patient. People should seek the second dose from their usual health care provider, regardless of where their initial dose was obtained.  

We are working with local community-based organizations to provide the vaccine to those who may not have access to the walk-in clinics or a healthcare provider. We will continue to keep the community updated on additional allocations of vaccines and access points. 

Vaccine supply remains limited. This unfortunately, means that someone may be eligible for a vaccine but unable to receive it immediately. 

The goal is for everyone who wants a vaccine to receive a vaccine. 

We will let the community know as soon as we have more doses of the vaccine. 


People who live or work in San Francisco are eligible for a Jynneos vaccine:    

  • Gay or bisexual men, or any man or trans person who has sex with men or trans people 

  • Sex workers of any sexual orientation or gender identity  

  • Persons of any age or any gender who have had close contact within the past 14 days with someone with suspected or confirmed MPX   

  • Persons who had close contact with others at a venue or event or within a social group in the past 14 days where a suspected or confirmed MPX case was identified. This includes persons who received notice from a venue or event of a potential exposure within the past 14 days  

  • Laboratory workers who routinely perform MPX virus testing  

  • Clinicians who have had a high-risk occupational exposure (e.g., examined MPX lesions or collected MPX specimens without using recommended personal protective equipment)  

If a person receives one dose, a second dose can be administered without having to restart the series, even if the second dose is given after the minimum interval of four weeks.   

Since no vaccine is 100 percent effective, it is important for individuals to reduce their risk of potential exposures to MPX both before and after being vaccinated.   

Temporary Expansion in Vaccine Eligibility to Visitors: September 18 to October 2 

We have received a special allotment from the Federal government to provide protection for people who are attending upcoming community-based and large, public events associated with the Folsom Street Fair and Castro Street Fair.   

The health and safety of those attending these large events, and socializing and celebrating locally because of these events, is essential, which is why from September 18 to October 2, we are temporarily expanding eligibility for the MPX (Jynneos) vaccine at San Francisco vaccine sites to also include eligible people who are visiting San Francisco. 

MPX Vaccine Sites

People should seek the second dose from their health care provider, regardless of where their first dose was obtained.  

Community Vaccine Events 

The vaccines, which includes first and second doses of Jynneos, will be available to eligible event attendees at various pop-up vaccination sites, neighborhood vaccine clinics, the Folsom Street Fair and Castro Street Fair, and events at health system providers. 

We are working with trusted community partners at various venues to reach communities most highly at risk and supporting pop-up vaccine clinics at neighborhood events.

  • 24 and Capp St. every Friday, Saturday and Monday from 9am to 3:45pm

  • Folsom Street Fair on September 25 from 10am to 4pm

  • Castro Street Fair on October 2

  • The vaccination clinic at ZSFG at 1001 Potrero, Building 30, will continue as a walk in clinic for both first and second doses. A limited number of second doses will be available Monday, September 26 through Friday, September 30 from 8am to 4pm or until vaccine supply is exhausted for each day. We will also be open on Saturday, October 1 from 8am to 3pm or until supply is exhausted. We will provide the community with updates as the situation develops.
  • SF Pride at El Rio, 3158 Mission Street from 4pm to 8pm on September 30, 4pm to 8pm on October 7, and 3pm to 7pm on October 14

The following locations have supplies of Jynneos vaccine by appointment only:    

  • Adult Immunization and Travel Clinic (AITC) patients: please make an online appointment at

  • SF City Clinic: call 628-217-6600

  • Strut patients: call 628-212-8038  

  • Kaiser Permanente patients and non-patients: call 415-833-9999  

  • SF Health Network patients: call your provider or health center directly 

  • UCSF patients and non-patients: call 415-502-3566 

How to get proof of MPX vaccination

Ask for documentation when you get vaccinated

Ask for a record of your vaccination when you get vaccinated.  This may be a yellow card or a print-out of your vaccination. There is no official ‘card’ for MPX vaccinations. Some vaccine sites use a ‘yellow card’, and others provide a print-out.


If you did not receive a record of your vaccination:

  • Check your medical record or ask your provider

    You can find it in your online health record under the immunization history section. If you don’t see it, ask your healthcare provider.  Your provider should have a record of vaccination dates and locations. They can also print your immunization record through the California Immunization Registry (CAIR)
  • Request a record from CAIR

    CAIR was not designed for a high volume of requests. Use this method if the above options are not possible. Requests may take up to 14 business days, so please plan ahead. The California Immunization Registry (CAIR) is a secure immunization information system for California. Fill out this form to get your record emailed to you. Travelers from outside the U.S. who get vaccinated in California may email the Help Desk to get the form. Residents of Alpine, Amador, Calaveras, Mariposa, Merced, San Joaquin, Stanislaus, and Tuolumne counties: Visit My Healthy Futures to get your immunization record.


When is it time for your second dose of MPX vaccine?

If this is your first dose, don’t forget to complete your 2nd dose! You should get your 2nd dose at 28 days or later after your first dose. You can set a reminder in your phone or mark your calendar. If you are not local, visit the MPX Vaccine Locator for locations near you.

Last updated September 23, 2022