Mpox Vaccine

Available to people of any age or gender who may have been exposed. We are now giving second doses after 28 days.

Mpox Vaccine

SF vaccine sites are now providing the second dose of the mpox (Jynneos) vaccine to people who are at least 28 days from receiving their first dose.

Mpox vaccines are available by appointment at healthcare providers and clinics throughout the city, including Kaiser Permanente (call 415-833-9999) and UCSF (call 415-502-3566). You do not need to be a Kaiser or UCSF Patient. People should seek the second dose from their usual health care provider, regardless of where their initial dose was obtained.  

We are working with local community-based organizations to provide the vaccine to those who may not have access to the walk-in clinics or a healthcare provider. We will continue to keep the community updated on additional allocations of vaccines and access points. 

The goal is for everyone who wants a vaccine to receive a vaccine. 

Mpox Vaccine Administration Update

SFDPH & partner sites are now offering first and second doses of the mpox vaccine though subcutaneous injection for eligible people who prefer this method over an intradermal injection. Both methods provide the same amount of protection against mpox. Click here to learn more about both methods. No matter the choice you make, it is important to get your second dose of the mpox vaccine if it has been at least 28 days since you received your first dose, to be fully vaccinated against mpox. 


People who live or work in San Francisco are eligible for a Jynneos vaccine:    

  • Gay or bisexual men, or any man, trans, or nonbinary person who has sex with men, trans, or nonbinary people

  • Sex workers of any sexual orientation or gender identity 

  • Persons of any age and any gender who have had close contact within the past 6 months with someone with suspected or confirmed mpox

  • Persons who had sex or close contact with others at a venue or event or within a social group within the past 6 months where a suspected or confirmed mpox case was identified. This includes persons who received notice from a venue or event of a potential exposure.

  • Persons living with HIV

  • Persons who are taking or are eligible to take HIV PrEP

  • Sexual contacts of any of the persons above 

  • Persons who anticipate experiencing any of the above

  • Laboratory workers who routinely perform mpox virus testing  

  • Clinicians who are likely to collect laboratory specimens from persons with mpox

  • Clinicians who have had a high-risk occupational exposure (e.g., examined mpox lesions or collected mpox specimens without using recommended personal protective equipment)  

If a person receives one dose, a second dose can be administered without having to restart the series, even if the second dose is given after the minimum interval of four weeks.   

Since no vaccine is 100 percent effective, it is important for individuals to reduce their risk of potential exposures to mpox both before and after being vaccinated.   

MPX Vaccine Sites

People should seek the second dose from their health care provider, regardless of where their first dose was obtained.  

The vaccines, which includes first and second doses of Jynneos, is available  at various pop-up vaccination sites, neighborhood vaccine clinics and events at health system providers. 

Vaccine Sites

The following locations have supplies of Jynneos vaccine by appointment only:    

  • Adult Immunization and Travel Clinic (AITC) patients: please make an online appointment at

  • SF City Clinic: call 628-217-6600

  • Strut patients: call 628-212-8038  

  • Kaiser Permanente patients and non-patients: call 415-833-9999  

  • SF Health Network patients: call your provider or health center directly 

  • UCSF patients and non-patients: call 415-502-3566 

How to get proof of Mpox vaccination


  • Check your medical record or ask your provider

    You can find it in your online health record under the immunization history section. If you don’t see it, ask your healthcare provider.  Your provider should have a record of vaccination dates and locations. They can also print your immunization record through the California Immunization Registry (CAIR)
  • Request a record from CAIR

    CAIR was not designed for a high volume of requests. Use this method if the above options are not possible. Requests may take up to 14 business days, so please plan ahead. The California Immunization Registry (CAIR) is a secure immunization information system for California. Fill out this form to get your record emailed to you. Travelers from outside the U.S. who get vaccinated in California may email the Help Desk to get the form. Residents of Alpine, Amador, Calaveras, Mariposa, Merced, San Joaquin, Stanislaus, and Tuolumne counties: Visit My Healthy Futures to get your immunization record.


When is it time for your second dose of MPX vaccine?

If this is your first dose, don’t forget to complete your 2nd dose! You should get your 2nd dose at 28 days or later after your first dose. You can set a reminder in your phone or mark your calendar. If you are not local, visit the MPX Vaccine Locator for locations near you.

Last updated December 7, 2022